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The unbalanced regulation of the glutathione synthesis coupled with the rapid and steady increase of glutathione abundance in the wheat tissue of the infested resistant plants suggested that the -glutamylcysteine synthetase might be either inhibited by a negative feedback from GSH, or it is not the rate-limiting enzyme in the glutathione synthetic pathway in wheat plants under our experimental conditions
falciparum standard in vitro culture conditions were conducted as previously described ( Eryptosis Assay and Flow Cytometry Analysis Previously described eryptosis inducers were selected for this study based on their use (or potential use) in the clinic, their known targets and/or their previously described antimalarial activity ( Table 1 ): amiodarone HCl (Selleck Chem, #S1979), apigenin (Selleck Chem, #S2262), BAY 43-9006 (AdipoGen Life Sciences, #AG-CR1-0025), benzethonium chloride (Selleck Chem, #S4162), cordycepin (Cayman Chemicals, #14426), ionomycin (ThermoFisher, #I24222) and oridonin (Selleck Chem, #S2335)
A delicate balance: Role of MMP-9 in brain development and pathophysiology of neurodevelopmental disorders
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